- Describe the general structure of an antibody (3 points)
- Write a short paragraph for each of the following antibody components: heavy chains, light chains, hypervariable regions, framework regions (8 points)
- Compare and contrast the terms affinity and avidity (4 points)
- What is meant by the term antibody subclass? (2 points)
- Describe what hybridomas and monoclonal antibodies are. How is monoclonal antibody specific for a defined antigen produced? Describe the process in detail. (6 points)
- How are antigenic determinants formed? Describe the difference between linear and conformational determinants. (4 points)
- What is the biologic significance of polyvalent interactions between antigen and antibody? (3 points)
